Journal
SYNTHETIC COMMUNICATIONS
Volume 44, Issue 12, Pages 1786-1794Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/00397911.2013.873467
Keywords
Ammonium chloride; one-pot condensation; 4(3H)-quinazolinones; solvent-free
Categories
Funding
- Applied Basic Research Projects of Yunnan Province [2013FZ043, 2014FZ042]
- Scientific Research Fund of Yunnan Education Department [22012Z017, 2013Y431]
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Ammonium chloride, which is a very inexpensive and readily available reagent, can efficiently catalyze three-component, one-pot condensation reactions of 2-amino-benzoic acid esters, ortho esters, and aromatic amines to afford the corresponding 4(3H)-quinazolinones in good to excellent yields under solvent-free conditions.
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