4.3 Article

RAPID SYNTHESIS OF POLYFUNCTIONALIZED PYRANO[2,3-c]PYRAZOLES VIA MULTICOMPONENT CONDENSATION IN ROOM-TEMPERATURE IONIC LIQUIDS

Journal

SYNTHETIC COMMUNICATIONS
Volume 41, Issue 3, Pages 405-410

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1080/00397910903576669

Keywords

1-Butyl-3-methylimidazolium tetrafloroborate; clean synthesis; combinatorial chemistry; heterocycles; pyrano[2,3-c]pyrazoles

Funding

  1. Council of Scientific and Industrial Research, New Delhi, India

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A highly efficient synthesis of 4H-pyrano[2,3-c]pyrazoles has been completed using four-component cyclocondensation of hydrazine monohydrate/phenyl hydrazine, ethyl acetoacetate, aldehydes, and malononitrile in the presence of L-proline and room-temperature ionic liquids.

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