Journal
SYNTHETIC COMMUNICATIONS
Volume 41, Issue 22, Pages 3280-3288Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/00397911.2010.517413
Keywords
alpha-Amino acids; 1,3-dipolar cycloaddition; isatin; 1,4-naphthoquinone
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Funding
- Natural Science Foundation of Jiangsu Province [BK2006048]
- Nature Science Key Basic Research of Jiangsu Province for Higher Education [06KJA15007]
- National Natural Science Foundation of China [20472062, 20672079]
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1,3-Dipolar cycloadditions involving 1,4-naphthoquinone and an azomethine ylide generated from a-amino acids and isatins have been used in this reaction to afford the pyrrolidine-2-spiro-3'-oxindole 4 or 5 with moderate to excellent yields.
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