Journal
SYNTHETIC COMMUNICATIONS
Volume 40, Issue 10, Pages 1418-1436Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/00397910903097260
Keywords
Analog synthesis for biological screening; 3; 7-dihydro-purine-2; 6-dione derivatives; substituted xanthines; xanthine derivatives
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Forty-six novel 3,7-dihydro-purine-2,6-dione derivatives (substituted xanthines) with great structural diversity were synthesized for biological activity screening. Three series of substituted xanthine analogs have been prepared in moderate to excellent yields.
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