Journal
SYNTHETIC COMMUNICATIONS
Volume 40, Issue 16, Pages 2389-2396Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/00397910903245166
Keywords
Aryl boronate; cycloisodityrosin; deoxybouvardin; palladium catalyst; ring closure
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A facile synthesis of the core cycloisodityrosine 14-membered ring system is detailed from commercially available L-tyrosine through a novel synthetic approach to aryl boronic acid 12 via intramolecular cyclization.
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