Journal
SYNTHETIC COMMUNICATIONS
Volume 40, Issue 9, Pages 1270-1275Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/00397910903068204
Keywords
MCM-41; multicomponent one-pot reactions; p-TsOH; tetra-substituted imidazoles
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Funding
- Azzahra Research Council
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An improved and rapid one-pot synthesis of tetrasubstituted imidazoles by condensing benzil, ammonium acetate, amines, and aromatic aldehydes and using a catalytic amount of silica structure MCM-41 or p-toluenesulfonic acid (p-TsOH) as efficient, green, reusable catalysts in excellent yields is reported.
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