Journal
SYNTHETIC COMMUNICATIONS
Volume 40, Issue 5, Pages 632-641Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/00397910902908822
Keywords
Aromatic aldehyde; aromatic o-aminonitrile; catalyst; cyclocondensation; one-pot synthesis
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Funding
- Beijing Municipal Commission of Education
- Beijing Institute of Technology
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An efficient synthetic method for the preparation of quinazolin-4-one derivatives was designed. The facile condensation of aromatic o-aminonitriles with aromatic aldehydes catalyzed by Lewis acid give 1,2-dihydroquinazolin-4(3H)-ones in moderate to good yields under refluxing dimethylformamide.
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