4.3 Article

Facile Method for One-Step Synthesis of 2,4,5-Triarylimidazoles Under Catalyst-Free, Solvent-Free, and Microwave-Irradiation Conditions

Journal

SYNTHETIC COMMUNICATIONS
Volume 40, Issue 8, Pages 1134-1141

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1080/00397910903043025

Keywords

Aromatic aldehyde; benzil; catalyst-free; microwave irradiation; solvent-free; triarylimidazole

Funding

  1. National Natural Science Foundation of China [20671038]
  2. Jiangsu Key Laboratory for Chemistry of Low-Dimensional Materials

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A green and efficient method for the synthesis of 2,4,5-triarylimidazoles by one-step condensation reaction of benzil, aromatic aldehyde, and ammonium acetate under catalyst-free, solvent-free, and microwave-irradiation conditions is reported. This method had many dramatic advantages, such as the short reaction time (3-5min), good yields (80-99%), environmental friendliness, and convenient operation.

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