Journal
SYNTHETIC COMMUNICATIONS
Volume 40, Issue 8, Pages 1115-1122Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/00397910903043009
Keywords
Biginelli reaction; copper nitrate; 3; 4-dihydropyrimidin-2(1H)-ones
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Funding
- National Nature Science Foundation of China [20772024, 20802016]
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The synthesis of 3,4-dihydropyrimidin-2-(1H)-ones derivatives via a three-component Biginelli reaction using copper nitrate as a catalyst under solventless conditions is reported, providing a green, rapid, efficient, and convenient method for the preparation of Biginelli compounds in good yields.
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