Journal
SYNTHETIC COMMUNICATIONS
Volume 39, Issue 7, Pages 1257-1263Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/00397910802517871
Keywords
Biginelli reaction; biosupported catalyst; cellulose sulfuric acid (CSA); 3; 4-dihydropyrimidin-2(1H)-ones; one-pot synthesis
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Biosupported cellulose sulfuric acid has been found to be an efficient solid acid catalyst for the one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones. The advantages of this method are avoidance of harsh reaction conditions, ecofriendly chemistry, operational simplicity, high yield, and reusable catalyst.
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