Journal
SYNTHETIC COMMUNICATIONS
Volume 39, Issue 17, Pages 3031-3037Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/00397910902730861
Keywords
Arylation; clioquinol; oxazolopyridine; palladium; synthesis
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Funding
- European Union for a Marie Curie fellowship [MIF1CT-2005-514549]
- PERCH-CIC, Faculty of Science, Mahasarakham University
- Leeds University
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5-Chloro-7-[1,3]oxazolo[4,5-b]pyridin-2-ylquinolin-8-ol was synthesized by a Pd-catalyzed arylation, which proceeds efficiently with 2 equivalents of benzylated clioquinol and 1 equivalent of oxazolo[4,5-b]pyridine. The product was smoothly debenzylated by boron trichloride in dichloromethane.
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