Journal
SYNTHETIC COMMUNICATIONS
Volume 39, Issue 15, Pages 2789-2794Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/00397910802664244
Keywords
Chalcones; Claisen-Schmidt condensation; green chemistry; grinding; solvent-free synthesis
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An improved Claisen-Schmidt condensation reaction of methyl ketones and aromatic aldehydes can be achieved by grinding at room temperature in the absence of solvents. This process is simple, efficient, economical, and environmentally benign compared to classical reactions.
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