Journal
SYNTHETIC COMMUNICATIONS
Volume 39, Issue 15, Pages 2702-2722Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/00397910802663436
Keywords
Carboxylic acids; Friedel-Crafts; P2O5; Al2O3
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An efficient and chemoselective method for the Friedel-Crafts acylation of aromatic compounds using P2O5/Al2O3 and carboxylic acids. Both aromatic and aliphatic carboxylic acids reacted easily to afford the corresponding aromatic ketones in good yields.
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