4.3 Article

Iodobenzene Diacetate Mediated Oxidation of N-Substituted Hydrazones of Chalcones: An Efficient Regioselective Synthesis of 1,3,5-Trisubstituted Pyrazoles

Journal

SYNTHETIC COMMUNICATIONS
Volume 39, Issue 12, Pages 2169-2177

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1080/00397910802640038

Keywords

Iodobenzene diacetate; oxidative cyclization; regioselective; N-substituted hydrazones of chalcones; 1; 3; 5-trisubstituted pyrazoles

Funding

  1. Council of Scientific and Industrial Research, New Delhi

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Iodobenzene diacetate, a relatively benign nonmetallic oxidant, has been utilized efficiently for the oxidation of N-substituted hydrazones of chalcones to afford 1,3,5-trisubstituted pyrazoles under mild reaction conditions.

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