Journal
SYNTHETIC COMMUNICATIONS
Volume 39, Issue 12, Pages 2101-2107Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/00397910802638511
Keywords
Aldehyde; iodine; multicomponent reaction; -naphthol; solvent-free conditions; xanthene
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Funding
- Hebei Normal University [L2008Y05]
- Nature Science Foundation of Hebei Province [B2008000149]
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Iodine efficiently catalyzes the one-pot, three-component reaction of aryl aldehyde, 2-naphthol, and cyclic 1,3-dicarbonyl compound under solvent-free conventional heating conditions to afford the corresponding 12-aryl-8,9,10,12-tetrahydro-benzo[a]xanthen-11-one derivatives. The present approach offers several advantages such as shorter reaction times, good yields, low cost, and mild reaction conditions.
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