Journal
SYNTHETIC COMMUNICATIONS
Volume 39, Issue 4, Pages 596-603Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/00397910802413865
Keywords
2-Aryl-2; 3-dihydro-4(1H)-quinolones; (dichloroiodo)benzene; regioselective chlorination
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Funding
- Council for Scientific and Industrial Research (CSIR), New Delhi
- Defense Research & Development Organization (DRDO), New Delhi [ERIP/ER/0303447/M/01]
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Oxidation of 2-aryl-2,3-dihydro-4(1H)-quinolones (1) with 1.5 equivalents of (dichloroiodo)benzene in dichloromethane at room temperature leads to regioselective chlorination, thereby offering an efficient method for the synthesis of new 2-aryl-6-chloro-2,3-dihydro-4(1H)-quinolones (3).
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