Journal
SYNTHETIC COMMUNICATIONS
Volume 38, Issue 18, Pages 3208-3214Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/00397910802109299
Keywords
condensation; inversion; mild conditions; one-pot; Vilsmeier reagent
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(Chloromethylene)dimethylammonium chloride (Vilsmeier reagent) works as an efficient condensation reagent in the formation of carboxylic esters from carboxylic acids and alcohols under mild conditions in a one-pot procedure. Secondary alcohols are converted successively into the corresponding esters in moderate to high yields with inversion of configurations.
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