4.3 Article

Dimethyl sulfoxide pivaloyl chloride: A new reagent for oxidation of alcohols to carbonyls

Journal

SYNTHETIC COMMUNICATIONS
Volume 38, Issue 5, Pages 746-753

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1080/00397910701820343

Keywords

alcohols; carbonyls; DMSO; pivaloyl chloride; Swern oxidation

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An efficient procedure for conversion of alcohols to the corresponding carbonyl compounds, an alternative to the classical Swern oxidation, is described. Pivaloyl chloride is employed as a mild and inexpensive electrophile. A possible reaction mechanism is proposed.

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