Synthesis of new 2-aryl substituted 2,3-dihydroquinazoline-4(1H)-ones under solvent-free conditions, using molecular iodine as a mild and efficient catalyst

A simple, inexpensive, and efficient one-pot synthesis of 2,3-dihydroquinazoline-4(1H)-one derivatives under solvent-free conditions using a catalytic amount of iodine with excellent product yields is reported. This methodology provides easy, quantitative access to various 2,3-dihydroquinazoline-4(1H)-one derivatives, using commercially available iodine as a catalyst.