4.3 Article

FeCl3-catalyzed nucleophilic substitution of Baylis-Hillman adducts with alcohols

Journal

SYNTHETIC COMMUNICATIONS
Volume 38, Issue 10, Pages 1617-1628

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1080/00397910801929622

Keywords

alcohol; Baylis-Hillman adduct; ether; FeCl3; nucleophilic substitution

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FeCl3-catalyzed nucleophilic substitution reaction of Baylis-Hillman adducts with alcohols is described. The present protocol allows for the efficient syntheses of many kinds of functional ethers. This conversion is also a green route because water is the only side product.

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