Journal
SYNTHESIS-STUTTGART
Volume 51, Issue 2, Pages 552-556Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0037-1610909
Keywords
total synthesis; goniothaline; Perkin reaction; silver-catalyzed cycloisomerization; selective demethylation
Categories
Funding
- National Research Foundation of Korea (NRF) - Ministry of Science, ICT & Future Planning [NRF-2017R1C1B1001826]
Ask authors/readers for more resources
In this paper, we report the first total synthesis of goniothaline A and B, which are rare natural pyridocoumarins isolated from Goniothalamus australis . The key feature of the synthesis of goniothaline A is high-yielding silver-catalyzed cycloisomerization to afford the pyridine moiety. In addition, goniothaline B, a natural 8-hydroxyquinoline derivative, is readily synthesized by the regioselective demethylation of goniothaline A.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available