4.5 Article

Oxidation of 1-Amidoalkyl-2-naphthols Using (Diacetoxyiodo)benzene: Unusual Formation of 1-Arylnaphtho[1,2-d]isoxazoles

Journal

SYNTHESIS-STUTTGART
Volume 46, Issue 6, Pages 752-756

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0033-1338590

Keywords

1,2-benzisoxazole; hypervalent iodine; 1-amidoalkyl-2-naphthols; 2-hydroxyaryl ketoximes; phenolic oxidation

Funding

  1. Department of Science and Technology, New Delhi, India [SR/S1/OC-72/2009]

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The reactions of 1-amidoalkyl-2-naphthols with (diacetoxyiodo)benzene results in the unusual formation of 1-arylnaphtho[1,2-d]isoxazoles. This procedure demonstrates a useful application of (diacetoxyiodo) benzene for the oxidative formation of an N-O bond.

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