4.5 Article

Catalyst-Free and Stereoselective Synthesis of N,N-Bicyclic Pyrazolidinone Derivatives

Journal

SYNTHESIS-STUTTGART
Volume 45, Issue 10, Pages 1325-1332

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0032-1316890

Keywords

N,N-bicyclic pyrazolidinone; azomethine imine; trans-beta-nitrostyrene; cycloaddition; stereoselectivity

Funding

  1. Shaanxi Provincial Natural Science Foundation of China [2009K01-51]

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A catalyst-free and stereoselective cycloaddition of pyrazolidin-3-one-derived azomethine imine to trans-beta-nitrostyrene is described, which allows versatile, efficient and highly enantioselective synthesis of N,N-bicyclic pyrazolidinone derivatives.

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