Journal
SYNTHESIS-STUTTGART
Volume 45, Issue 14, Pages 1909-1930Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0033-1338484
Keywords
organocatalysis; domino reactions; multicomponent reactions; cyclohexanes; cyclohexenes; asymmetric synthesis
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Funding
- Agence Nationale pour la Recherche [ANR-11-BS07-0014]
- Centre National de la Recherche Scientifique (CNRS)
- Aix-Marseille Universite
- Agence Nationale de la Recherche (ANR) [ANR-11-BS07-0014] Funding Source: Agence Nationale de la Recherche (ANR)
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Polysubstituted chiral cyclohexanes and cyclohexenes are important building blocks in organic synthesis. From historical and pioneering reports to the most recent accounts, this review focuses on domino enantioselective organocatalytic methodologies that have allowed the control of the relative and absolute configurations of up to six stereogenic centers in the construction of these versatile molecular architectures.
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