4.5 Article

Copper-Catalyzed Oxidation of Deoxybenzoins to Benzils under Aerobic Conditions

Journal

SYNTHESIS-STUTTGART
Volume 45, Issue 12, Pages 1701-1707

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0033-1338451

Keywords

copper; catalysis; oxidation; deoxybenzoins; benzils

Funding

  1. MURST
  2. University 'La Sapienza', Rome

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A novel copper-catalyzed approach to benzils from readily available deoxybenzoins under neutral conditions using air as the oxidant has been developed. The reaction tolerates a variety of useful substituents including chloro, bromo, iodo, keto, ester, and cyano groups.

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