Journal
SYNTHESIS-STUTTGART
Volume 44, Issue 8, Pages 1237-1246Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0031-1289731
Keywords
nitrogen heterocycles; multicomponent reactions; sulfinylations; thiols; bond activation
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Funding
- National Natural Science Foundation of China [20962010, 21162012]
- Jiangxi Provincial Department of Science and Technology (for Jiangxi's Key Laboratory of Green Chemistry)
- Science Foundation of Education Department of Jiangxi province [GJJ10386]
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The direct sulfanylation of 2-aryl-4-quinazolinones with thiols via C-OH bond activation under mild conditions is described. The method affords the corresponding 2-aryl-4-sulfanylquinazolines in good to excellent yield.
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