Journal
SYNTHESIS-STUTTGART
Volume 44, Issue 21, Pages 3361-3365Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0032-1317340
Keywords
niobium pentachloride; multicomponent reaction; coumarin derivatives; Lewis acid; phenols
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Funding
- Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [Procs. 2010/18022-2]
- Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)
- Coordenadoria de Aperfeicoamento de Pessoal do Nivel Superior (CAPES)
- Pro-Reitoria de Pesquisa da UNESP (PROPe-UNESP)
- Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP) [10/18022-2] Funding Source: FAPESP
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Substituted 4-aryl-3,4-dihydrocoumarins are synthesized from multicomponent reactions between phenols, dimethyl malonate, and aryl aldehydes catalyzed by niobium pentachloride. This new method is simple, cost-effective, and high-yielding, and can be conducted in acceptable reaction times.
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