4.5 Article

Tandem Decarboxylative Allylation and Fragmentation of Allyl Benzocyclobutenyl Carbonates: Access to ortho-Functionalized Aryls from Aryl Bromides

Journal

SYNTHESIS-STUTTGART
Volume 44, Issue 12, Pages 1885-1891

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0031-1290943

Keywords

benzocyclobutenol; decarboxylative allylation; palladium; fragmentation; strain release

Funding

  1. York University
  2. Natural Sciences and Engineering Research Council of Canada

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Allyl benzocyclobutyl carbonates yield ortho-allyl alpha-aryl ketones through a palladium-catalyzed decarboxylative allylation, fragmentation, and cross-coupling process.

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