Journal
SYNTHESIS-STUTTGART
Volume 45, Issue 2, Pages 141-152Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0032-1316812
Keywords
fluorine; fluorine compounds; optical purification; chiral recognition; chromatography; physicochemical phase transitions; amino acids; amines; hydroxy acids
Categories
Funding
- IKERBASQUE, Basque Foundation for Science
Ask authors/readers for more resources
This review discusses all available literature on the self-disproportionation of enantiomers (SDE) of fluorine-containing compounds, resulting in a separation of racemic form from the excess enantiomer. Included are examples of the SDE via distillation, sublimation and achiral chromatography. The role of fluorine on the magnitude and preparative efficiency of the SDE, as a new, nonconventional method for optical purifications, is emphasized and critically discussed. 1 Introduction 2 General Aspects of Fluorine Influence on the Self-Disproportionation of Enantiomers 3 Self-Disproportionation of Enantiomers via Distillation 4 Self-Disproportionation of Enantiomers via Sublimation 5 Self-Disproportionation of Enantiomers via Achiral Chromatography 6 Conclusions
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available