Journal
SYNTHESIS-STUTTGART
Volume -, Issue 4, Pages 662-668Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0030-1258408
Keywords
alkene; catalysis; cobalt; diene; regioselectivity
Categories
Funding
- Deutsche Forschungsgemeinschaft
Ask authors/readers for more resources
The substrate-directed regiochemistry of the cobalt-catalysed 1,4-hydrovinylation reaction is described. A variety of symmetrical and unsymmetrical 2,3-disubstituted 1,3-dienes are synthesised by ruthenium-catalysed enyne metathesis, and then reacted with a terminal alkene catalysed by cobalt(II) bromide-[1,2-bis(diphenylphosphino)ethane] [CoBr2(dppe)] under reductive conditions. The regiochemistry of the branched 1,4-diene products is influenced by the nature of the substituents on the unsymmetrical 2,3-disubstituted 1,3-dienes. The influence of steric and electronic effects is also discussed.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available