4.5 Article

Synthesis of Coumarins and Neoflavones through Zinc Chloride Catalyzed Hydroarylation of Acetylenic Esters with Phenols

Journal

SYNTHESIS-STUTTGART
Volume -, Issue 22, Pages 3692-3696

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0031-1289576

Keywords

phenols; catalysis; arylations; heterocycles; alkynes; esters

Funding

  1. FAPERJ
  2. CNPq
  3. CAPES

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Acetylenic esters react with oxygenated phenols under solvent-free conditions in the presence of only 5 mol% of zinc chloride as a catalyst to give coumarins and neoflavones in reasonable-to-good yields.

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