4.5 Article

A Facile and Efficient Synthesis of 2-Imidazolines from Aldehydes Using Hydrogen Peroxide and Substoichiometric Sodium Iodide

Journal

SYNTHESIS-STUTTGART
Volume -, Issue 10, Pages 1599-1603

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0030-1259992

Keywords

2-imidazoline; hydrogen peroxide; aldehydes; ethylenediamine; environmentally friendly process

Funding

  1. National Natural Science Foundation of China [20806018]
  2. Hebei Education Department [ZD200910]

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The reaction of aldehydes with ethylenediamine for the preparation of 2-imidazolines has been studied using hydrogen peroxide as an oxidant in the presence of sodium iodide and anhydrous magnesium sulfate. A mild, green, and efficient method is established to carry out this reaction in high yield.

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