Journal
SYNTHESIS-STUTTGART
Volume -, Issue 8, Pages 1229-1279Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0029-1218699
Keywords
cinchona alkaloids; organocatalysis; asymmetric catalysis; kinetic resolution; stereoselective synthesis
Categories
Funding
- MIUR
- Politecnico di Milano
- NRSC-C (National Research School Combination - Catalysis) at the University of Amsterdam
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This article reviews the applications of cinchona alkaloids as asymmetric catalysts. In the last few years, characterized by the resurgence of interest in asymmetric organocatalysis, cinchona derivatives have been shown to catalyze an outstanding array of chemical reactions, often with remarkable stereoselectivity. This work presents an overview of the transformations developed in the period from 2001 through 2009, highlighting applications in the synthesis of bioactive molecules and natural products.
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