4.5 Article

Novel Mono- and Bis(spiro-2-amino-4H-pyrans): Alum-Catalyzed Reaction of 4-Hydroxycoumarin and Malononitrile with Isatins, Quinones, or Ninhydrin

Journal

SYNTHESIS-STUTTGART
Volume -, Issue 10, Pages 1731-1735

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0029-1219748

Keywords

alum [KAl(SO4)(2)center dot 12H(2)O]; spiro-2-amino-4H-pyrans; 4-hydroxycoumarin

Funding

  1. Research Council of Arak University

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Some new mono- and bis(spiro-2-amino-4H-pyrans) are synthesized by the multicomponent condensation reaction of 4-hydroxycoumarin and malononitrile with isatins, ninhydrin, 9,10-phenanthrenequinone, or acenaphthenequinone. Alum was found to be a suitable and efficient catalyst for this condensation.

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