4.5 Article

Efficient Synthesis of Azaspirodienones by Microwave-Assisted Radical Spirocyclization of Xanthate-Containing Ugi Adducts

Journal

SYNTHESIS-STUTTGART
Volume -, Issue 8, Pages 1285-1290

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0029-1218700

Keywords

Ugi reaction; cyclizations; spiro compounds; lactams; microwave reactions

Funding

  1. CONCYTEG [GTO-2003C02- 11945]
  2. CONACYT [J42673Q, J50922]

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The sequential use of an Ugi reaction and radical spirocyclization under microwave irradiation conditions is described. The process provides rapid access to spirodienone lactams.

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