4.4 Article

Photoredox-Catalyzed Decarboxylative C-H Acylation of Heteroarenes

Journal

SYNLETT
Volume 29, Issue 14, Pages 1881-1886

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0037-1609911

Keywords

2,2-diethoxyacetic acid; alpha-keto acids; heterocycles; C-H functionalization; acylation

Funding

  1. China NSFC [21372055, 21472030, 21672047]
  2. SKLUWRE [2018DX02]

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A mild, environmentally friendly, and regioselective acylation of heterocycles with inexpensive carboxylic acids is reported via photoredox catalysis. The strategy is highlighted with good functional group tolerance and substrate scope which could rapidly realize the acylation of various heterocyclic compounds.

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