Journal
SYNLETT
Volume 25, Issue 9, Pages 1307-1311Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0033-1341057
Keywords
metal-free; trifluoromethylation; ketones; alcohols; Langlois reagent; styrenes
Categories
Funding
- NSF of Jiangxi Provincial Education Department [GJJ12570, KJLD13081]
- China Scholarship Council
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A mild and practical protocol for the metal-free trifluoromethylation of styrenes using NaSO2CF3 (Langlois reagent) and TBHP was developed. The approach provides efficient access to -trifluoromethylated ketones and alcohols in moderate to good yields.
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