Journal
SYNLETT
Volume 26, Issue 1, Pages 51-54Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0034-1378915
Keywords
organofluorine; fluoroheterocycle; pyrazole; selective fluorination; fluoropyrazole
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Fluorination of 3,5-diarylpyrazole substrates by Selectfluor (TM) in acetonitrile gave 4,4-difluoro-1H-pyrazoles in addition to 4-fluoropyrazole derivatives. The structure of this new class of fluorinated heterocycle was established by X-ray crystallography.
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