4.4 Article

Solvent-Free Condensation of Phenols with Aldehydes and Amides Using 3-Methyl-1-sulfonic Acid Imidazolium Chloride

Journal

SYNLETT
Volume 25, Issue 8, Pages 1173-1177

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0033-1340984

Keywords

amidoalkyl phenol; ionic liquid; sulfonic acid functionalized imidazolium salts; SAFIS; phenol; aldehyde; solvent-free

Funding

  1. Research Affairs Office of Bu-Ali Sina University [32-1716]
  2. Center of Excellence in Development of Chemical Method (CEDCM), Hamedan, I.R. Iran

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One-pot, three-component condensation of phenols, aromatic aldehydes, and amides in the presence of 3-methyl-1-sulfonic acid imidazolium chloride {[Msim]Cl} as ionic liquid and catalyst under solvent-free condition to prepare a new category of compounds, namely amido-alkyl-phenols has been described. In the presented work, all products have been reported for the first time.

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