Journal
SYNLETT
Volume 24, Issue 10, Pages 1205-1210Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0033-1338956
Keywords
N-heterocyclic carbenes; catalysis; immobilization; amides; solid-phase synthesis
Categories
Funding
- European Research Council [ERC] [306793 - CASAA]
- ETH Zurich
Ask authors/readers for more resources
We have prepared an oligomeric histidine-bound N-heterocyclic carbene precursor by coupling a carboxylic acid functionalized 1,2,4-triazolium salt to a peptide using solid-phase peptide synthesis. We have demonstrated that the resulting multifunctional resin-bound catalyst cooperatively facilitates redox amidation reactions of aldehydes and amines, a reaction not catalyzed by N-heterocyclic carbenes alone.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available