4.4 Article

Stereoselective Synthesis of Fluoroalkylated Butanolides

Journal

SYNLETT
Volume 24, Issue 18, Pages 2383-2388

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0033-1339755

Keywords

fluorine; fluoroalkylation; lactones; stereoselective synthesis; chiral auxiliaries

Funding

  1. DFG [Graduiertenkolleg 1582]

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Starting from fluoroalkylated, optically active acyl oxazolidinones the corresponding di- and trisubstituted butanolides were prepared in enantiomerically pure form. Using a divergent synthetic route highly functionalized fluoroalkylated building blocks are accessible.

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