4.4 Article

Copper-Catalyzed Cyanation of Arylboronic Acids Using DDQ as Cyanide Source

Journal

SYNLETT
Volume -, Issue 15, Pages 2247-2250

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0031-1290451

Keywords

copper; cyanation; arylboronic acids; nitriles; DDQ

Funding

  1. National Natural Science Foundation of China [20972115]
  2. Natural Science Foundation of Zhejiang Province [LY12B02010, R4110294]
  3. Priority Academic Program Development of Jiangsu Higher Education Institutions

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In this paper, a copper-catalyzed cyanation of arylboronic acids is achieved with DDQ, providing nitriles with good yields. This new approach represents a safe method for the synthesis of aryl nitriles.

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