Journal
SYNLETT
Volume -, Issue 15, Pages 2171-2176Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0030-1261205
Keywords
C-H bond activation; directing group; indoles; iridium; ureas
Categories
Funding
- MEXT, Japan
- Waseda University, Japan
Ask authors/readers for more resources
Secondary sp(3) C-H bond activation of ureas was achieved by a cationic Ir(I)-JOSIPHOS catalyst. Regioselective C-H bond cleavage adjacent to the nitrogen atom in N-benzylureas and an N-allyl urea possessing a 2-alkynylphenyl group, and subsequent intramolecular reaction with an alkyne along with double-bond isomerization provided 2,3-disubstituted indoles.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available