4.4 Article

Palladium-Catalyzed, One-Pot, Three-Component Approach to α-Alkynyl Indoles from o-Bromo-(2,2-dibromovinyl)benzenes, Terminal Alkynes and Arylamines

Journal

SYNLETT
Volume -, Issue 7, Pages 911-914

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0030-1259699

Keywords

multi-component coupling; o-halo-(2,2-dihalovinyl)benzene; alkyne; arylamine; indole; palladium-catalyzed reaction

Funding

  1. NSFC
  2. Postdoctorate Research Fund of China [20090460144]

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alpha-Alkynyl indoles were efficiently synthesized in one pot from o-bromo-(2,2-dibromovinyl)benzenes, terminal alkynes, and arylamines via a palladium-catalyzed three-component coupling process.

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