4.4 Article

Direct Sequential C-O and C-C Formation via Double sp2 C-H Bond Activations to Construct 6H-Benzo[c]chromen-6-ones

Journal

SYNLETT
Volume -, Issue 7, Pages 883-886

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0030-1259724

Keywords

C-H bond activation; ortho acyloxylation; 6H-benzo[c]chromen-6-one

Funding

  1. Peking University
  2. National Sciences of Foundation of China [20542001, 20521202, 20672006]
  3. MOST of China [2009CB825300]

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A new method for the direct ortho acyloxylation of sp(2) C-H bond with various carboxylic acids was developed. A novel strategy to synthesize 6H-benzo[c]chromen-6-one derivatives was designed via Pd-catalyzed double activations of adjacent sp(2) C-H bonds.

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