4.4 Article

Catalytic Enantioselective Synthesis of 3-Substituted Benzosultams via Corey-Bakshi-Shibata Reduction of Cyclic N-Sulfonylimines

Journal

SYNLETT
Volume -, Issue 3, Pages 402-404

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-0030-1259314

Keywords

asymmetric synthesis; imine; reduction; catalysis; sulfonamide

Funding

  1. Fonds der Chemischen Industrie

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The catalytic asymmetric synthesis of 3-substituted benzo-fused sultams employing the Corey-Bakshi-Shibata reduction with catecholborane of the corresponding cyclic N-sulfonylimines is reported. Good to excellent yields (74-95%) and enantiomeric excesses (69-94%) are obtained.

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