Journal
SYNLETT
Volume -, Issue 3, Pages 323-326Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0030-1259318
Keywords
Mannich reaction; organocatalysis; calcium; BINOL phosphoric acid; amino acid
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Funding
- Evonik Degussa
- DFG
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Asymmetric calcium-catalyzed direct Mannich reactions of 1,3-dicarbonyl compounds with imines have been developed. The reactions proceed under mild conditions and provide the corresponding products with high enantiomeric excess.
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