Journal
SYNLETT
Volume -, Issue 15, Pages 2157-2162Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0030-1261200
Keywords
microwave assisted; ytterbium triflate; one-pot; multicomponent; quinolines; ionic liquid
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Funding
- Department of Science and Technology, New Delhi
- BITS Pilani
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A straightforward and efficient method has been developed for the synthesis of quinolines by Yb(OTf)(3) catalyzed three-component reaction of aldehydes, alkynes, and amines under microwave irradiation in ionic liquid. A series of 2,4-disubstituted quinolines was synthesized in excellent yield (69-93%) under mild reaction condition and the catalyst was recycled for four cycles.
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