Journal
SYNLETT
Volume -, Issue 8, Pages 1179-1183Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0030-1259954
Keywords
pyrimidine; propargylation; amidine; copper; annulation
Categories
Funding
- National Natural Science Foundation of China [21072159]
- Science & Technology Bureau of Xiamen [3502Z20093007]
- NFFTBS [J1030415]
Ask authors/readers for more resources
A new approach to the tandem synthesis of 2,4-disubstituted or 2,4,6-trisubstituted pyrimidines from propargylic alcohols with amidine is described. This reaction is catalyzed by 20 mol% Cu(OTf)(2) to give pyrimidines in moderate to good yields via a propargylation-cyclization-oxidation tandem sequence.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
