Journal
SYNLETT
Volume -, Issue 17, Pages 2575-2578Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0030-1258768
Keywords
aza-hetero-Diels-Alder reaction; Lewis acid catalysis; Schiff base; Pyrido[3,2-d)]pyrimidine; 5-amino-1,3-dimethyl uracil
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Funding
- CSIR (New Delhi)
- DST (New Delhi)
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Pyrido[3,2-d]pyrimidine derivatives have been synthesized by the hetero-Diels-Alder reaction of 5-amino-1,3-dimethyl uracil and O-propargylated salicylaldehyde. The reaction requires only a single-step operation and provides potentially bioactive polycyclic heterocycles in high yields (71-82%) from easily available starting materials.
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